НачалоЗа лекариQuality of sexual life in men with lifelong premature ejaculation treated with dapoxetine

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Genov P. 1 , Kolev N. 2 , Dunev V. 2 , Stoykov B. 2 , Vanov A. 2 , Atanasov J.2

1MHAT Ruse, Dept. of Urology, Ruse, Bulgaria, 2UMHAT , Dept. of Urology, Pleven, Bulgaria

 

Introduction & Objectives: Although premature ejaculation (PE) is a common male sexual dysfunction, it is poorly understood. Men with PE report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less frequent intercourse. However, the negative impact of PE extends beyond sexual dysfunction. PE can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. Our aim was to investigate the quality of sexual life in men with lifelong PE treated with dapoxetine, using the Brief Male Sexual Functional Inventory (BMSFI).

 Materials & Methods: Between September 2014 and March 2016 we include 52 patients with lifelong premature ejaculation taking 30 or 60 mg dapoxetine as needed, which were followed for 1 year. The BMSFI questionnaire was completed at the beginning of the treatment, on the 3-rd, 6-th and 12-th months.

Results: 24 points was the mean result in patients before treatment from BMSFI indicating significant worsening of sexual function and quality of life in all five questionnaire domains. At the third month timepoint, the score rises to 32 points, indicating high patient satisfaction shortly after the onset of treatment. The sixth and twelve months of onset of treatment maintained a steady tendency to increase the score, respectively 37 and 40 points. The results in the domain of ejaculation have changed and increased most rapidly and clearly, but they also increased the results in all other domains, showing a higher end-to-date satisfaction of patients from their sexual life.

Conclusions: Premature ejaculation worsens the overall sexual function and quality of life of patients and leads to problems in controlling ejaculation. Improving control and lengthening ejaculation time by using dapoxetine leads to higher overall patient satisfaction in all aspects of sexual function and life.

Eur Urol Suppl 2017; 16(11);e2829

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